| Gene Information | |
|---|---|
| Gene Name | CAND1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1230 |
| Protein Names | Cullin-associated NEDD8-dissociated protein 1 (Cullin-associated and neddylation-dissociated protein 1) (TBP-interacting protein of 120 kDa A) (TBP-interacting protein 120A) (p120 CAND1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000111530 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86VP6 |
| Gene Card | CAND1 |
| Uniprot ID | Q86VP6 |
| Pfam | PF08623 |
| In ASD | no |
| Allosteric Prediction | no (-0.909324653) |
| Ortholog in Animals | Alpaca_ CAND1 ( ortholog_one2one ) Dog_ CAND1 ( ortholog_one2one ) GuineaPig_ CAND1 ( ortholog_one2one ) Macaque_ CAND1 ( ortholog_one2one ) Mouse_ Cand1 ( ortholog_one2one ) Pig_ CAND1 ( ortholog_one2one ) Rat_ Cand1 ( ortholog_one2one ) Rabbit_ CAND1 ( ortholog_one2one ) |
| Ohnologs | CAND2 |
| Paralogs | CAND2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.013343(Chimpanzee);0.015867(Mouse);0.001899(Rat);0.050000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1U6G (X-ray 3.10A ) 4A0C (X-ray 3.80A ) |
| DBSNP | rs12580996 rs17854618 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21249194}. Nucleus {ECO:0000269|PubMed:21249194}. Note=Predominantly cytoplasmic. |
| Mouse PG classification | NA |
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