| Gene Information | |
|---|---|
| Gene Name | CAN |
| Organism | Homo sapiens (Human) |
| Gene Length | 2090 |
| Protein Names | Nuclear pore complex protein Nup214 (214 kDa nucleoporin) (Nucleoporin Nup214) (Protein CAN) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P35658 |
| Gene Card | NUP214 |
| Uniprot ID | P35658 |
| Pfam | PF18617 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in thymus, spleen, bone marrow, kidney, brain and testis, but hardly in all other tissues or in whole embryos during development. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001323(Rat);0.038889(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2OIT (X-ray 1.65A ) 3FHC (X-ray 2.80A ) 3FMO (X-ray 2.51A ) 3FMP (X-ray 3.19A ) 5DIS (X-ray 2.85A ) 7R5K (EM 12.00A ) |
| DBSNP | rs143595616 rs1564175808 rs563025075 rs103612 rs777822003 rs28594669 |
| Subcellular location [CC] | Nucleus, nuclear pore complex {ECO:0000269|PubMed:8108440}. Note=Cytoplasmic side of the nuclear pore complex. {ECO:0000269|PubMed:8108440}. |
| Mouse PG classification | NA |
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