Gene Information
Gene NameCAMP
OrganismHomo sapiens (Human)
Gene Length170
Protein NamesCathelicidin antimicrobial peptide (18 kDa cationic antimicrobial protein) (CAP-18) (hCAP-18) [Cleaved into: Antibacterial peptide FALL-39 (FALL-39 peptide antibiotic); Antibacterial peptide LL-37; Antibacterial peptide KR-20; Antibacterial peptide LL-23; Antibacterial peptide LL-29; Antibacterial peptide KS-30; Antibacterial peptide RK-31; Antibacterial peptide FF-33]
Target Namecathelicidin antimicrobial peptide
Target TypeNA
Gene Age70 ( ENSG00000164047 )
Evolutionary StageVertebrata
AlphaFoldDBP49913
Gene CardCAMP
Uniprot IDP49913
PfamPF12153
In ASDno
Allosteric Predictionyes (0.340162761)
Ortholog in AnimalsAlpaca_ CAMP ( ortholog_one2one )
Dog_ CAMP ( ortholog_one2one )
Macaque_ CAMP ( ortholog_one2one )
Mouse_ Camp ( ortholog_one2one )
Pig_ NPG3 ( ortholog_one2many )
Pig_ PMAP-36 ( ortholog_one2many )
Pig_ NPG1 ( ortholog_one2many )
Pig_ PG-2 ( ortholog_one2many )
Rat_ Camp ( ortholog_one2one )
Rabbit_ CAMP ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuebone.marrow, lung, spleen, whole.blood
Tissue SpecificityExpressed in neutrophilic granulocytes (at protein level) (PubMed:7890387, PubMed:8946956, PubMed:9736536, PubMed:7529412, PubMed:7615076, PubMed:8681941). Expressed in bone marrow (PubMed:7890387). {ECO:0000269|PubMed:7529412, ECO:0000269|PubMed:7615076, ECO:0000269|PubMed:7890387, ECO:0000269|PubMed:8681941, ECO:0000269|PubMed:8946956, ECO:0000269|PubMed:9736536}.;
[Antibacterial peptide LL-37]: Expressed in granulocytes (at protein level) (PubMed:8681941). Expressed by the eccrine apparatus and secreted into sweat on skin (at protein level) (PubMed:14978112). {ECO:0000269|PubMed:14978112, ECO:0000269|PubMed:8681941}.;
[Antibacterial peptide FALL-39]: Expressed in bone marrow and testis. {ECO:0000269|PubMed:7529412}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2FBS  (NMR  -  )  2FBU  (NMR  -  )  2FCG  (NMR  -  )  2K6O  (NMR  -  )  2LMF  (NMR  -  )  2NA3  (NMR  -  )  4EYC  (X-ray  1.90A  )  5NMN  (X-ray  0.95A  )  5NNK  (X-ray  1.80A  )  5NNM  (X-ray  1.90A  )  5NNT  (X-ray  2.21A  )  5XNG  (NMR  -  )  5XRX  (NMR  -  )  6BIV  (X-ray  2.90A  )  6BIX  (X-ray  2.20A  )  6S6M  (X-ray  1.35A  )  7NPQ  (X-ray  1.50A  )  7PDC  (X-ray  1.83A  )  7SAY  (X-ray  2.10A  ) 
DBSNP NA 
Subcellular location [CC]Secreted {ECO:0000269|PubMed:14978112}. Vesicle {ECO:0000269|PubMed:7529412, ECO:0000269|PubMed:9736536}. Note=Stored as pro-peptide in granules and phagolysosomes of neutrophils (PubMed:9736536, PubMed:7529412). Secreted in sweat onto skin (PubMed:14978112). {ECO:0000269|PubMed:14978112, ECO:0000269|PubMed:7529412, ECO:0000269|PubMed:9736536}.
Mouse PG classificationNA
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