| Gene Information | |
|---|---|
| Gene Name | CPB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 417 |
| Protein Names | Carboxypeptidase B (EC 3.4.17.2) (Pancreas-specific protein) (PASP) |
| Target Name | carboxypeptidase b1 |
| Target Type | Patented-recorded target |
| Gene Age | 950 ( ENSG00000153002 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | P15086 |
| Gene Card | CPB1 |
| Uniprot ID | P15086 |
| Pfam | PF00246; PF02244 |
| In ASD | no |
| Allosteric Prediction | yes (0.426704579) |
| Ortholog in Animals | Alpaca_ CPB1 ( ortholog_one2one ) GuineaPig_ CPB1 ( ortholog_one2one ) Macaque_ CPB1 ( ortholog_one2one ) Mouse_ Cpb1 ( ortholog_one2one ) Pig_ CPB1 ( ortholog_one2one ) Rat_ Cpb1 ( ortholog_one2one ) Rabbit_ CPB1 ( ortholog_one2one ) |
| Ohnologs | CPB2, CPA1, CPA4, CPA2, CPA5, CPA6 |
| Paralogs | CPO, CPA2, CPA6, CPA3, CPA4, CPB2, CPA5, CPA1 |
| Tissue | pancreas |
| Tissue Specificity | Pancreas. {ECO:0000269|PubMed:2920728}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1KWM (X-ray 1.60A ) 1ZLI (X-ray 2.09A ) |
| DBSNP | rs1059502 |
| Subcellular location [CC] | Secreted {ECO:0000250|UniProtKB:P00732}. Zymogen granule lumen {ECO:0000250|UniProtKB:P55261}. |
| Mouse PG classification | NA |
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