| Gene Information | |
|---|---|
| Gene Name | CAMKK1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 505 |
| Protein Names | Calcium/calmodulin-dependent protein kinase kinase 1 (CaM-KK 1) (CaM-kinase kinase 1) (CaMKK 1) (EC 2.7.11.17) (CaM-kinase IV kinase) (Calcium/calmodulin-dependent protein kinase kinase alpha) (CaM-KK alpha) (CaM-kinase kinase alpha) (CaMKK alpha) |
| Target Name | calcium/calmodulin-dependent protein kinase kinase 1 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000004660 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q8N5S9 |
| Gene Card | CAMKK1 |
| Uniprot ID | Q8N5S9 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.029658243) |
| Ortholog in Animals | Alpaca_ CAMKK1 ( ortholog_one2one ) Dog_ CAMKK1 ( ortholog_one2one ) GuineaPig_ CAMKK1 ( ortholog_one2one ) Macaque_ CAMKK1 ( ortholog_one2one ) Mouse_ Camkk1 ( ortholog_one2one ) Pig_ CAMKK1 ( ortholog_one2one ) Rat_ Camkk1 ( ortholog_one2one ) Rabbit_ CAMKK1 ( ortholog_one2one ) |
| Ohnologs | CAMKK2 |
| Paralogs | DCLK3, PHKG1, MYLK4, CAMKK2, DCLK2, PSKH1, PNCK, CAMK1D, CAMKV, CAMK2B, CAMK1, STK11, STK33, PHKG2, DCLK1, PSKH2, CAMK2G, MYLK2, CAMK2D, CAMK2A, MYLK3, CAMK1G |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6CCF (X-ray 2.10A ) 6CD6 (X-ray 2.20A ) |
| DBSNP | rs7214723 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. |
| Mouse PG classification | NA |
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