Gene Information
Gene NameTSPAN6
OrganismHomo sapiens (Human)
Gene Length245
Protein NamesTetraspanin-6 (Tspan-6) (A15 homolog) (Putative NF-kappa-B-activating protein 321) (T245 protein) (Tetraspanin TM4-D) (Transmembrane 4 superfamily member 6)
Target NameNA
Target TypeNA
Gene Age645 ( ENSG00000000003 )
Evolutionary StageEumetazoa
AlphaFoldDBO43657
Gene CardTSPAN6
Uniprot IDO43657
PfamPF00335
In ASDno
Allosteric Predictionno (-0.269603213)
Ortholog in AnimalsAlpaca_ TSPAN6 ( ortholog_one2one )
Dog_ TSPAN6 ( ortholog_one2one )
GuineaPig_ TSPAN6 ( ortholog_one2one )
Mouse_ Tspan6 ( ortholog_one2one )
Pig_ TSPAN6 ( ortholog_one2one )
Rat_ Tspan6 ( ortholog_one2one )
Rabbit_ TSPAN6 ( ortholog_one2one )
OhnologsTSPAN7, TSPAN3
ParalogsROM1, TSPAN12, CD63, TSPAN10, CD9, TSPAN5, CD37, CD151, TSPAN4, TSPAN1, TSPAN31, UPK1A, TSPAN17, TSPAN11, TSPAN32, TSPAN8, TSPAN13, TSPAN2, CD53, TSPAN9, TSPAN18, CD81, CD82, TSPAN16, TSPAN19, TSPAN7, UPK1B, TSPAN3, TSPAN14, TSPAN15, PRPH2, TSPAN33
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs1802288 
Subcellular location [CC]Membrane;
Multi-pass membrane protein.
Mouse PG classificationNA
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