Gene Information
Gene NameOTOP3
OrganismHomo sapiens (Human)
Gene Length596
Protein NamesProton channel OTOP3 (Otopetrin-3)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000182938 )
Evolutionary StageEumetazoa
AlphaFoldDBQ7RTS5
Gene CardOTOP3
Uniprot IDQ7RTS5
PfamPF03189
In ASDno
Allosteric Predictionno (-0.499159868)
Ortholog in AnimalsAlpaca_ OTOP3 ( ortholog_one2one )
Dog_ OTOP3 ( ortholog_one2one )
GuineaPig_ OTOP3 ( ortholog_one2one )
Macaque_ OTOP3 ( ortholog_one2one )
Mouse_ Otop3 ( ortholog_one2one )
Pig_ OTOP3 ( ortholog_one2one )
Rat_ Otop3 ( ortholog_one2one )
OhnologsNA
ParalogsOTOP2, OTOP1
Tissueduodenum, small.intestine
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs7210616  rs9890664  rs1542752  rs35131040 
Subcellular location [CC]Cell membrane {ECO:0000250|UniProtKB:Q80VM9};
Multi-pass membrane protein {ECO:0000255}.
Mouse PG classificationNA
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