| Gene Information | |
|---|---|
| Gene Name | CALM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 149 |
| Protein Names | Calmodulin-2 |
| Target Name | calmodulin-2 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000143933 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P0DP24 |
| Gene Card | CALM2 |
| Uniprot ID | P0DP24 |
| Pfam | PF13499 |
| In ASD | no |
| Allosteric Prediction | yes (0.56462477) |
| Ortholog in Animals | Alpaca_ CALM2 ( ortholog_one2one ) Dog_ CALM3 ( ortholog_one2one ) Mouse_ Calm2 ( ortholog_one2one ) Pig_ CALM2 ( ortholog_one2one ) Rat_ Calm-ps2 ( ortholog_one2many ) Rat_ Calm2 ( ortholog_one2many ) Rabbit_ CALM2 ( ortholog_one2one ) |
| Ohnologs | CALM3, CALM1 |
| Paralogs | CABP2, EFCAB7, CALN1, EFCAB3, CABP7, CETN3, CALML5, CETN1, CALML6, CABP4, CALML4, CABP1, CABP5, CETN2, EFCAB12, EFCAB2, EFCAB9, CALML3, CALM3, CALM1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001102(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | 3O77 (X-ray 2.35A ) 3O78 (X-ray 2.60A ) 5COC (X-ray 2.67A ) 5J03 (X-ray 2.00A ) 5NIN (X-ray 1.70A ) 5VMS (EM 3.70A ) 5WSU (X-ray 3.00A ) 5WSV (X-ray 2.33A ) 6PLM (X-ray 2.59A ) 6S5T (EM 4.15A ) 6SZ5 (X-ray 2.23A ) 6XXF (X-ray 1.70A ) 6Y4O (X-ray 1.84A ) 7MIR (EM 2.50A ) 7MIS (EM 2.80A ) 7PPO (EM 2.91A ) 7PQE (EM 3.70A ) |
| DBSNP | rs730882254 rs398124647 rs398124647 rs1573214163 rs398124648 rs398124650 rs398124649 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:16760425}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:16760425}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:14654843}. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules. |
| Mouse PG classification | NA |
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