| Gene Information | |
|---|---|
| Gene Name | ARHGAP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 439 |
| Protein Names | Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000175220 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q07960 |
| Gene Card | ARHGAP1 |
| Uniprot ID | Q07960 |
| Pfam | PF13716; PF00620 |
| In ASD | no |
| Allosteric Prediction | yes (0.031904837) |
| Ortholog in Animals | Alpaca_ ARHGAP1 ( ortholog_one2one ) Dog_ ARHGAP1 ( ortholog_one2one ) GuineaPig_ ARHGAP1 ( ortholog_one2one ) Macaque_ ARHGAP1 ( ortholog_one2one ) Mouse_ Arhgap1 ( ortholog_one2one ) Pig_ ARHGAP1 ( ortholog_one2one ) Rat_ Arhgap1 ( ortholog_one2one ) Rabbit_ ARHGAP1 ( ortholog_one2one ) |
| Ohnologs | PRR5 |
| Paralogs | ARHGAP8 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.030769(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1AM4 (X-ray 2.70A ) 1GRN (X-ray 2.10A ) 1OW3 (X-ray 1.80A ) 1RGP (X-ray 2.00A ) 1TX4 (X-ray 1.65A ) 2NGR (X-ray 1.90A ) 5M6X (X-ray 2.40A ) 5M70 (X-ray 2.20A ) 6R3V (X-ray 1.75A ) |
| DBSNP | rs11822837 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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