| Gene Information | |
|---|---|
| Gene Name | CALCA |
| Organism | Homo sapiens (Human) |
| Gene Length | 141 |
| Protein Names | Calcitonin [Cleaved into: Calcitonin; Katacalcin (Calcitonin carboxyl-terminal peptide) (CCP) (PDN-21)] |
| Target Name | calcitonin gene-related peptide 1 |
| Target Type | Clinical trial target |
| Gene Age | 101 ( ENSG00000110680 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P01258 |
| Gene Card | CALCA |
| Uniprot ID | P01258 |
| Pfam | PF00214 |
| In ASD | no |
| Allosteric Prediction | yes (0.708149059) |
| Ortholog in Animals | Alpaca_ CALCA ( ortholog_one2one ) Dog_ CRSP-4 ( ortholog_one2many ) Dog_ CRSP-3 ( ortholog_one2many ) Dog_ CRSP-2 ( ortholog_one2many ) Macaque_ CALCA ( ortholog_one2one ) Mouse_ Calca ( ortholog_one2one ) Rat_ Calca ( ortholog_one2one ) Rabbit_ CALCA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IAPP, CALCB |
| Tissue | thyroid, pineal.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2JXZ (NMR - ) 7TYH (EM 3.30A ) 7TYO (EM 2.70A ) |
| DBSNP | rs34587547 rs5239 rs34164367 rs5241 rs34414857 rs13306224 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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