| Gene Information | |
|---|---|
| Gene Name | PKMYT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 499 |
| Protein Names | Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (EC 2.7.11.1) (Myt1 kinase) |
| Target Name | membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000127564 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q99640 |
| Gene Card | PKMYT1 |
| Uniprot ID | Q99640 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.055945277) |
| Ortholog in Animals | Alpaca_ PKMYT1 ( ortholog_one2one ) Dog_ PKMYT1 ( ortholog_one2one ) GuineaPig_ PKMYT1 ( ortholog_one2one ) Macaque_ PKMYT1 ( ortholog_one2one ) Mouse_ Pkmyt1 ( ortholog_one2one ) Pig_ PKMYT1 ( ortholog_one2one ) Rat_ Pkmyt1 ( ortholog_one2one ) Rabbit_ PKMYT1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | STK35, EIF2AK3, EIF2AK4, WEE2, EIF2AK2, WEE1, PDIK1L, EIF2AK1 |
| Tissue | bone.marrow, testis |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.182081(Chimpanzee);0.079990(Mouse);0.002612(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3P1A (X-ray 1.70A ) 5VCV (X-ray 1.92A ) 5VCW (X-ray 2.25A ) 5VCX (X-ray 2.70A ) 5VCY (X-ray 1.56A ) 5VCZ (X-ray 1.50A ) 5VD0 (X-ray 2.13A ) 5VD1 (X-ray 1.70A ) 5VD3 (X-ray 1.80A ) 8D6C (X-ray 2.20A ) 8D6D (X-ray 2.35A ) 8D6E (X-ray 2.15A ) 8D6F (X-ray 2.49A ) |
| DBSNP | rs55834293 rs4149796 rs35192104 rs56382954 rs4149800 rs10546 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000269|PubMed:9001210}; Peripheral membrane protein {ECO:0000269|PubMed:9001210}. Golgi apparatus membrane {ECO:0000269|PubMed:9001210}; Peripheral membrane protein {ECO:0000269|PubMed:9001210}. |
| Mouse PG classification | NA |
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