Gene Information
Gene NameCADM4
OrganismHomo sapiens (Human)
Gene Length388
Protein NamesCell adhesion molecule 4 (Immunoglobulin superfamily member 4C) (IgSF4C) (Nectin-like protein 4) (NECL-4) (TSLC1-like protein 2)
Target NameNA
Target TypeNA
Gene Age454 ( ENSG00000105767 )
Evolutionary StageEumetazoa
AlphaFoldDBQ8NFZ8
Gene CardCADM4
Uniprot IDQ8NFZ8
PfamPF08205; PF07686
In ASDno
Allosteric Predictionno (-1.205061223)
Ortholog in AnimalsAlpaca_ CADM4 ( ortholog_one2one )
Dog_ CADM4 ( ortholog_one2one )
GuineaPig_ CADM4 ( ortholog_one2one )
Macaque_ CADM4 ( ortholog_one2one )
Mouse_ Cadm4 ( ortholog_one2one )
Pig_ CADM4 ( ortholog_one2one )
Rat_ Cadm4 ( ortholog_one2one )
Rabbit_ CADM4 ( ortholog_one2one )
OhnologsCADM2, CADM1
ParalogsTIGIT, NCR3, CD200, NECTIN1, NECTIN2, CADM3, NECTIN4, CADM2, CRTAM, NECTIN3, SMAGP, CADM1, CD226, PVR
TissueNA
Tissue SpecificityExpressed in brain, prostate, brain, kidney and some other organs. {ECO:0000269|PubMed:11536053, ECO:0000269|PubMed:16261159}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs34246023 
Subcellular location [CC]Membrane {ECO:0000305};
Single-pass type I membrane protein {ECO:0000305}.
Mouse PG classificationNA
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