| Gene Information | |
|---|---|
| Gene Name | IREB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 963 |
| Protein Names | Iron-responsive element-binding protein 2 (IRE-BP 2) (Iron regulatory protein 2) (IRP2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000136381 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P48200 |
| Gene Card | IREB2 |
| Uniprot ID | P48200 |
| Pfam | PF00330; PF00694 |
| In ASD | no |
| Allosteric Prediction | yes (0.178568513) |
| Ortholog in Animals | Alpaca_ IREB2 ( ortholog_one2one ) Dog_ IREB2 ( ortholog_one2one ) GuineaPig_ IREB2 ( ortholog_one2one ) Macaque_ IREB2 ( ortholog_one2one ) Mouse_ Ireb2 ( ortholog_one2one ) Pig_ IREB2 ( ortholog_one2one ) Rat_ Ireb2 ( ortholog_one2one ) Rabbit_ IREB2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ACO1, ACO2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.028016(Chimpanzee);0.001000(Mouse);NULL(Rat);0.036364(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6VCD (EM 3.00A ) |
| DBSNP | rs2230940 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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