| Gene Information | |
|---|---|
| Gene Name | CADM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 435 |
| Protein Names | Cell adhesion molecule 2 (Immunoglobulin superfamily member 4D) (IgSF4D) (Nectin-like protein 3) (NECL-3) (Synaptic cell adhesion molecule 2) (SynCAM 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000175161 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N3J6 |
| Gene Card | CADM2 |
| Uniprot ID | Q8N3J6 |
| Pfam | PF08205; PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.123952012) |
| Ortholog in Animals | Alpaca_ CADM2 ( ortholog_one2one ) Dog_ CADM2 ( ortholog_one2one ) GuineaPig_ CADM2 ( ortholog_one2one ) Macaque_ CADM2 ( ortholog_one2one ) Mouse_ Cadm2 ( ortholog_one2one ) Pig_ CADM2 ( ortholog_one2one ) Rat_ Cadm2 ( ortholog_one2one ) Rabbit_ CADM2 ( ortholog_one2one ) |
| Ohnologs | PVR, CADM4, NECTIN2 |
| Paralogs | TIGIT, NCR3, CD200, NECTIN1, NECTIN2, CADM3, NECTIN4, CRTAM, NECTIN3, CADM4, SMAGP, CADM1, CD226, PVR |
| Tissue | brain, cerebral.cortex |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:17967169}; Single-pass type I membrane protein {ECO:0000269|PubMed:17967169}. Synapse {ECO:0000269|PubMed:17967169}. Cell projection, axon {ECO:0000269|PubMed:17967169}. Note=Found in the axoplasm of myelinated axons. |
| Mouse PG classification | NA |
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