| Gene Information | |
|---|---|
| Gene Name | TPSG1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 321 |
| Protein Names | Tryptase gamma (EC 3.4.21.-) (Serine protease 31) (Transmembrane tryptase) [Cleaved into: Tryptase gamma light chain; Tryptase gamma heavy chain] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 78 ( ENSG00000116176 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9NRR2 |
| Gene Card | TPSG1 |
| Uniprot ID | Q9NRR2 |
| Pfam | PF00089 |
| In ASD | no |
| Allosteric Prediction | no (-0.453930403) |
| Ortholog in Animals | Alpaca_ TPSG1 ( ortholog_one2one ) Macaque_ TPSG1 ( ortholog_one2one ) Mouse_ Tpsg1 ( ortholog_one2one ) Rat_ Tpsg1 ( ortholog_one2one ) |
| Ohnologs | TMPRSS3, TMPRSS13 |
| Paralogs | TPSD1, TPSAB1, TPSB2 |
| Tissue | colon, duodenum |
| Tissue Specificity | Expressed in many tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs760357 rs4984638 rs11248860 rs1004041 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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