Gene Information
Gene NameE2IG3
OrganismHomo sapiens (Human)
Gene Length549
Protein NamesGuanine nucleotide-binding protein-like 3 (E2-induced gene 3 protein) (Novel nucleolar protein 47) (NNP47) (Nucleolar GTP-binding protein 3) (Nucleostemin)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9BVP2
Gene CardGNL3
Uniprot IDQ9BVP2
PfamPF08701; PF01926
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityIncreased levels in lung tissue in cancer patients. {ECO:0000269|PubMed:16012751}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.002186(Rat);0.307556(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs11177  rs2289247 
Subcellular location [CC]Nucleus {ECO:0000250|UniProtKB:Q811S9}. Nucleus, nucleolus {ECO:0000269|PubMed:11790298, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:12464630}. Note=Shuttles between the nucleus and nucleolus. {ECO:0000250|UniProtKB:Q811S9}.
Mouse PG classificationNA
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