| Gene Information | |
|---|---|
| Gene Name | FIGN |
| Organism | Homo sapiens (Human) |
| Gene Length | 759 |
| Protein Names | Fidgetin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000182263 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q5HY92 |
| Gene Card | FIGN |
| Uniprot ID | Q5HY92 |
| Pfam | PF00004; PF09336 |
| In ASD | no |
| Allosteric Prediction | no (-1.189310189) |
| Ortholog in Animals | Alpaca_ FIGN ( ortholog_one2one ) Dog_ FIGN ( ortholog_one2one ) GuineaPig_ FIGN ( ortholog_one2one ) Macaque_ FIGN ( ortholog_one2one ) Mouse_ Fign ( ortholog_one2one ) Pig_ FIGN ( ortholog_one2one ) Rat_ Fign ( ortholog_one2one ) Rabbit_ FIGN ( ortholog_one2one ) |
| Ohnologs | FIGNL1 |
| Paralogs | FIGNL2, VPS4A, ATAD1, FIGNL1, KATNAL2, SPAST, VPS4B, KATNAL1, KATNA1 |
| Tissue | substantia.nigra |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2231902 rs2231904 rs2231905 |
| Subcellular location [CC] | Nucleus matrix {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:22672901}. Note=Localizes to centrosomes throughout mitosis and to the spindle midzone during telophase. |
| Mouse PG classification | NA |
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