| Gene Information | |
|---|---|
| Gene Name | ALS2CL |
| Organism | Homo sapiens (Human) |
| Gene Length | 953 |
| Protein Names | ALS2 C-terminal-like protein |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000178038 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q60I27 |
| Gene Card | ALS2CL |
| Uniprot ID | Q60I27 |
| Pfam | PF02493; PF02204 |
| In ASD | no |
| Allosteric Prediction | no (-1.469794298) |
| Ortholog in Animals | Alpaca_ ALS2CL ( ortholog_one2one ) Dog_ ALS2CL ( ortholog_one2one ) GuineaPig_ ALS2CL ( ortholog_one2one ) Macaque_ ALS2CL ( ortholog_one2one ) Mouse_ Als2cl ( ortholog_one2one ) Pig_ ALS2CL ( ortholog_one2one ) Rat_ Als2cl ( ortholog_one2one ) Rabbit_ ALS2CL ( ortholog_one2one ) |
| Ohnologs | ALS2 |
| Paralogs | RSPH10B2, RSPH10B, SETD7, MORN2, RSPH1, MORN1, MORN3 |
| Tissue | NA |
| Tissue Specificity | Expressed in heart and kidney. {ECO:0000269|PubMed:15388334}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs59661801 rs7642448 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:15388334, ECO:0000269|PubMed:17239822}. Note=Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells. |
| Mouse PG classification | NA |
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