| Gene Information | |
|---|---|
| Gene Name | CACNB3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 484 |
| Protein Names | Voltage-dependent L-type calcium channel subunit beta-3 (CAB3) (Calcium channel voltage-dependent subunit beta 3) |
| Target Name | voltage-dependent calcium channel |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000167535 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P54284 |
| Gene Card | CACNB3 |
| Uniprot ID | P54284 |
| Pfam | PF00625; PF12052 |
| In ASD | no |
| Allosteric Prediction | yes (0.79131603) |
| Ortholog in Animals | Alpaca_ CACNB3 ( ortholog_one2one ) Dog_ CACNB3 ( ortholog_one2one ) GuineaPig_ CACNB3 ( ortholog_one2one ) Macaque_ CACNB3 ( ortholog_one2one ) Mouse_ Cacnb3 ( ortholog_one2one ) Pig_ CACNB3 ( ortholog_one2one ) Rat_ Cacnb3 ( ortholog_one2one ) Rabbit_ CACNB3 ( ortholog_one2one ) |
| Ohnologs | CACNB1, CACNB2, CACNB4 |
| Paralogs | CACNB4, CACNB2, CACNB1 |
| Tissue | NA |
| Tissue Specificity | Expressed mostly in brain, colon and ovary. {ECO:0000269|PubMed:8119293}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.015385(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 7MIX (EM 3.00A ) 7MIY (EM 3.10A ) 7UHF (EM 3.10A ) 7UHG (EM 3.00A ) |
| DBSNP | rs2229954 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:34234349}. |
| Mouse PG classification | NA |
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