| Gene Information | |
|---|---|
| Gene Name | CACNB2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 660 |
| Protein Names | Voltage-dependent L-type calcium channel subunit beta-2 (CAB2) (Calcium channel voltage-dependent subunit beta 2) (Lambert-Eaton myasthenic syndrome antigen B) (MYSB) |
| Target Name | voltage-dependent l-type calcium channel |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000165995 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q08289 |
| Gene Card | CACNB2 |
| Uniprot ID | Q08289 |
| Pfam | PF00625; PF12052 |
| In ASD | no |
| Allosteric Prediction | yes (0.928939669) |
| Ortholog in Animals | Alpaca_ CACNB2 ( ortholog_one2one ) Dog_ CACNB2 ( ortholog_one2one ) GuineaPig_ Cacnb2 ( ortholog_one2one ) Macaque_ CACNB2 ( ortholog_one2one ) Mouse_ Cacnb2 ( ortholog_one2one ) Pig_ CACNB2 ( ortholog_one2one ) Rat_ Cacnb2 ( ortholog_one2one ) Rabbit_ CACNB2 ( ortholog_one2one ) |
| Ohnologs | CACNB1, CACNB3, CACNB4 |
| Paralogs | CACNB4, CACNB3, CACNB1 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs745502425 rs121917812 |
| Subcellular location [CC] | Cell membrane, sarcolemma {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |