| Gene Information | |
|---|---|
| Gene Name | ITGA10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1167 |
| Protein Names | Integrin alpha-10 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000143127 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | O75578 |
| Gene Card | ITGA10 |
| Uniprot ID | O75578 |
| Pfam | PF01839; PF08441; PF00092 |
| In ASD | no |
| Allosteric Prediction | no (-0.382094742) |
| Ortholog in Animals | Alpaca_ ITGA10 ( ortholog_one2one ) Dog_ ITGA10 ( ortholog_one2one ) GuineaPig_ ITGA10 ( ortholog_one2one ) Macaque_ ITGA10 ( ortholog_one2one ) Mouse_ Itga10 ( ortholog_one2one ) Pig_ ITGA10 ( ortholog_one2one ) Rat_ Itga10 ( ortholog_one2one ) Rabbit_ ITGA10 ( ortholog_one2one ) |
| Ohnologs | ITGAL, ITGA11, ITGAX, ITGAD, ITGA2, ITGAM, ITGA1 |
| Paralogs | ITGA4, ITGAX, ITGAE, ITGA2, ITGAD, ITGA5, ITGA6, ITGAV, ITGA7, ITGA8, ITGAL, ITGA3, ITGA2B, ITGA11, ITGA1, ITGAM, ITGA9 |
| Tissue | bone.marrow, dura.mater, mitral.valve |
| Tissue Specificity | Widely expressed with highest expression in muscle and heart. Found in articular cartilage. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6665210 rs36073645 rs2274618 rs35515885 rs2274616 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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