| Gene Information | |
|---|---|
| Gene Name | CACNA1I |
| Organism | Homo sapiens (Human) |
| Gene Length | 2223 |
| Protein Names | Voltage-dependent T-type calcium channel subunit alpha-1I (Voltage-gated calcium channel subunit alpha Cav3.3) (Ca(v)3.3) |
| Target Name | voltage-dependent t-type calcium channel |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000100346 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9P0X4 |
| Gene Card | CACNA1I |
| Uniprot ID | Q9P0X4 |
| Pfam | PF00520 |
| In ASD | yes |
| Allosteric Prediction | yes (1.080904891) |
| Ortholog in Animals | Alpaca_ CACNA1I ( ortholog_one2one ) Dog_ CACNA1I ( ortholog_one2one ) GuineaPig_ CACNA1I ( ortholog_one2one ) Macaque_ CACNA1I ( ortholog_one2one ) Mouse_ Cacna1i ( ortholog_one2one ) Pig_ CACNA1I ( ortholog_one2one ) Rat_ Cacna1i ( ortholog_one2one ) |
| Ohnologs | CACNA1G |
| Paralogs | SCN11A, CACNA1C, CATSPER1, CACNA1E, SCN9A, CACNA1B, SCN7A, SCN3A, SCN5A, SCN2A, SCN1A, CACNA1A, CACNA1F, CACNA1H, CATSPER2, CACNA1G, SCN8A, NALCN, CACNA1D, CATSPER4, SCN10A, CACNA1S, CATSPER3, TPCN1, TPCN2, SCN4A |
| Tissue | NA |
| Tissue Specificity | Brain specific. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 7WLI (EM 3.30A ) 7WLJ (EM 3.90A ) 7WLK (EM 3.60A ) 7WLL (EM 3.60A ) |
| DBSNP | rs136853 rs8141262 rs2294369 rs2294369 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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