| Gene Information | |
|---|---|
| Gene Name | RNF114 |
| Organism | Homo sapiens (Human) |
| Gene Length | 228 |
| Protein Names | E3 ubiquitin-protein ligase RNF114 (EC 2.3.2.27) (RING finger protein 114) (RING-type E3 ubiquitin transferase RNF114) (Zinc finger protein 228) (Zinc finger protein 313) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000124226 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9Y508 |
| Gene Card | RNF114 |
| Uniprot ID | Q9Y508 |
| Pfam | PF05605; PF13445; PF18574 |
| In ASD | no |
| Allosteric Prediction | no (-0.930069885) |
| Ortholog in Animals | Alpaca_ RNF114 ( ortholog_one2one ) Dog_ RNF114 ( ortholog_one2one ) GuineaPig_ RNF114 ( ortholog_one2one ) Macaque_ RNF114 ( ortholog_one2one ) Mouse_ Rnf114 ( ortholog_one2one ) Pig_ RNF114 ( ortholog_one2one ) Rat_ Rnf114 ( ortholog_one2one ) Rabbit_ RNF114 ( ortholog_one2one ) |
| Ohnologs | RNF138, RNF166 |
| Paralogs | RNF138, RNF125, RNF166, RNF180 |
| Tissue | NA |
| Tissue Specificity | Expressed in numerous tissues, including skin, CD4 lymphocytes and dendritic cells. Highest levels in testis. {ECO:0000269|PubMed:18364390}. |
| Pharmacological Animal Models | 0.020968(Chimpanzee);0.027573(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:23645206}. Nucleus {ECO:0000269|PubMed:23645206}. |
| Mouse PG classification | NA |
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