| Gene Information | |
|---|---|
| Gene Name | CACNA1F |
| Organism | Homo sapiens (Human) |
| Gene Length | 1977 |
| Protein Names | Voltage-dependent L-type calcium channel subunit alpha-1F (Voltage-gated calcium channel subunit alpha Cav1.4) |
| Target Name | voltage-dependent l-type calcium channel |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000102001 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O60840 |
| Gene Card | CACNA1F |
| Uniprot ID | O60840 |
| Pfam | PF08763; PF16885; PF16905; PF00520 |
| In ASD | no |
| Allosteric Prediction | yes (0.906684717) |
| Ortholog in Animals | Alpaca_ CACNA1F ( ortholog_one2one ) Dog_ CACNA1F ( ortholog_one2one ) GuineaPig_ CACNA1F ( ortholog_one2one ) Macaque_ CACNA1F ( ortholog_one2one ) Mouse_ Cacna1f ( ortholog_one2one ) Pig_ CACNA1F ( ortholog_one2one ) Rat_ Cacna1f ( ortholog_one2one ) Rabbit_ CACNA1F ( ortholog_one2one ) |
| Ohnologs | CACNA1S, CACNA1C, CACNA1D |
| Paralogs | SCN11A, CACNA1C, CATSPER1, CACNA1E, CACNA1I, SCN9A, CACNA1B, SCN7A, SCN3A, SCN5A, SCN2A, SCN1A, CACNA1A, CACNA1H, CATSPER2, CACNA1G, SCN8A, NALCN, CACNA1D, CATSPER4, SCN10A, CACNA1S, CATSPER3, TPCN1, TPCN2, SCN4A |
| Tissue | pineal.gland |
| Tissue Specificity | Expression in skeletal muscle and retina (PubMed:10873387). Isoform 4 is expressed in retina (PubMed:27226626). {ECO:0000269|PubMed:10873387, ECO:0000269|PubMed:27226626}. |
| Pharmacological Animal Models | 0.170437(Chimpanzee);0.137144(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6520408 rs122456133 rs34162630 rs201654095 rs141010716 rs141159097 rs1602644716 rs122456136 rs1249437161 rs34308720 rs34308720 rs33910054 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | HPG |
| click here to return to the previous page | |