| Gene Information | |
|---|---|
| Gene Name | SYT10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 523 |
| Protein Names | Synaptotagmin-10 (Synaptotagmin X) (SytX) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000110975 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q6XYQ8 |
| Gene Card | SYT10 |
| Uniprot ID | Q6XYQ8 |
| Pfam | PF00168 |
| In ASD | no |
| Allosteric Prediction | no (-0.499702445) |
| Ortholog in Animals | Alpaca_ SYT10 ( ortholog_one2one ) Dog_ SYT10 ( ortholog_one2one ) GuineaPig_ SYT10 ( ortholog_one2one ) Macaque_ SYT10 ( ortholog_one2one ) Mouse_ Syt10 ( ortholog_one2one ) Pig_ SYT10 ( ortholog_one2one ) Rat_ Syt10 ( ortholog_one2one ) Rabbit_ SYT10 ( ortholog_one2one ) |
| Ohnologs | SYT3, SYT6, SYT9 |
| Paralogs | SYT2, SYTL3, SYT13, TC2N, SYT1, SYT7, SYTL4, SYTL5, DOC2B, DOC2A, SYT14, C2CD4C, SYTL1, RPH3A, SYT8, SYT4, SYT11, SYT12, C2CD4A, C2CD4B, RPH3AL, SYT15, SYT15B, SYT9, SYT16, SYT6, C2CD4D, SYT3, SYTL2, SYT5, SYT17 |
| Tissue | NA |
| Tissue Specificity | Expressed only in pancreas, lung and kidney. {ECO:0000269|PubMed:14756426}. |
| Pharmacological Animal Models | 0.140380(Chimpanzee);0.117317(Mouse);NULL(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12317722 rs35190376 rs34190017 rs34361405 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle membrane {ECO:0000250|UniProtKB:Q9R0N4}; Single-pass membrane protein {ECO:0000255}. Note=Localizes to neuronal vesicles containing IGF1 that are not enriched at synapses. Does not colocalize with synaptic vesicles or with the Golgi apparatus. {ECO:0000250|UniProtKB:Q9R0N4}. |
| Mouse PG classification | NA |
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