| Gene Information | |
|---|---|
| Gene Name | CACH3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2161 |
| Protein Names | Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q01668 |
| Gene Card | CACNA1D |
| Uniprot ID | Q01668 |
| Pfam | PF08763; PF16885; PF16905; PF00520 |
| In ASD | yes |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in pancreatic islets and in brain, where it has been seen in cerebral cortex, hippocampus, basal ganglia, habenula and thalamus. Expressed in the small cell lung carcinoma cell line SCC-9. No expression in skeletal muscle. {ECO:0000269|PubMed:1335101}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.096977(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3LV3 (X-ray 1.94A ) 7UHF (EM 3.10A ) 7UHG (EM 3.00A ) |
| DBSNP | rs1163276899 rs41276445 rs41276455 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:18482979}; Multi-pass membrane protein {ECO:0000269|PubMed:18482979}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |