| Gene Information | |
|---|---|
| Gene Name | CABYR |
| Organism | Homo sapiens (Human) |
| Gene Length | 493 |
| Protein Names | Calcium-binding tyrosine phosphorylation-regulated protein (Calcium-binding protein 86) (Cancer/testis antigen 88) (CT88) (Fibrousheathin II) (Fibrousheathin-2) (FSP-2) (Testis-specific calcium-binding protein CBP86) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000154040 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O75952 |
| Gene Card | CABYR |
| Uniprot ID | O75952 |
| Pfam | PF02197 |
| In ASD | no |
| Allosteric Prediction | no (-1.215755473) |
| Ortholog in Animals | Alpaca_ CABYR ( ortholog_one2one ) Dog_ CABYR ( ortholog_one2one ) GuineaPig_ CABYR ( ortholog_one2one ) Macaque_ CABYR ( ortholog_one2one ) Mouse_ Cabyr ( ortholog_one2one ) Pig_ CABYR ( ortholog_one2one ) Rat_ Cabyr ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | testis |
| Tissue Specificity | Expressed in elongating spermatids and spermatozoa (at protein level). Isoform 1 is expressed in testis. Isoform 3 and isoform 5 are also expressed in brain, pancreas and numerous brain tumors. {ECO:0000269|PubMed:11820818, ECO:0000269|PubMed:15752768, ECO:0000269|PubMed:16139264}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3786417 rs35118855 rs1049682 rs1049683 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Note=Localized to fibrous sheath including the surface of the longitudinal columns and ribs of the principal piece of sperm flagella.; [Isoform 1]: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.; [Isoform 3]: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic.; [Isoform 5]: Nucleus. Cytoplasm. Cell projection, cilium, flagellum. Note=According to PubMed:15752768, isoform 1, isoform 3 and isoform 5 are both nuclear and cytoplasmic. |
| Mouse PG classification | NA |
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