| Gene Information | |
|---|---|
| Gene Name | BPIFB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 484 |
| Protein Names | BPI fold-containing family B member 1 (Long palate, lung and nasal epithelium carcinoma-associated protein 1) (von Ebner minor salivary gland protein) (VEMSGP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 244 ( ENSG00000125999 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q8TDL5 |
| Gene Card | BPIFB1 |
| Uniprot ID | Q8TDL5 |
| Pfam | PF01273; PF02886 |
| In ASD | no |
| Allosteric Prediction | no (-1.066901334) |
| Ortholog in Animals | Alpaca_ BPIFB1 ( ortholog_one2one ) Dog_ BPIFB1 ( ortholog_one2one ) GuineaPig_ BPIFB1 ( ortholog_one2one ) Macaque_ BPIFB1 ( ortholog_one2one ) Mouse_ Bpifb1 ( ortholog_one2one ) Pig_ BPIFB1 ( ortholog_one2one ) Rat_ Bpifb1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | BPIFA1, BPIFA3, BPIFA2, BPIFB2, BPIFB6, BPIFB4, BPIFB3, BPI, PLTP, LBP, CETP, BPIFC |
| Tissue | stomach, duodenum, lung, urinary.bladder, minor.salivary.gland |
| Tissue Specificity | Detected in duodenum mucosal crypts of cholera patients, near Paneth cells (at protein level). Detected in trachea, nasal septal epithelium and lung. {ECO:0000269|PubMed:21900486}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs1078761 rs34578060 rs6141383 rs34548457 rs6120221 rs6120222 rs17856249 rs1999663 |
| Subcellular location [CC] | Secreted {ECO:0000250}. |
| Mouse PG classification | NA |
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