| Gene Information | |
|---|---|
| Gene Name | CAB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 445 |
| Protein Names | StAR-related lipid transfer protein 3 (Metastatic lymph node gene 64 protein) (MLN 64) (Protein CAB1) (START domain-containing protein 3) (StARD3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q14849 |
| Gene Card | STARD3 |
| Uniprot ID | Q14849 |
| Pfam | PF10457; PF01852 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in retina. {ECO:0000269|PubMed:21322544}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1EM2 (X-ray 2.20A ) 5I9J (X-ray 1.74A ) 6TQR (X-ray 1.85A ) 6TQU (X-ray 2.40A ) |
| DBSNP | rs1877031 rs11556624 |
| Subcellular location [CC] | Late endosome membrane {ECO:0000269|PubMed:11053434, ECO:0000269|PubMed:16709157, ECO:0000269|PubMed:24105263, ECO:0000269|PubMed:28377464, ECO:0000269|PubMed:29858488}; Multi-pass membrane protein {ECO:0000255}. Note=Localizes to contact sites between the endoplasmic reticulum and late endosomes: associates with the endoplasmic reticulum membrane via interaction with VAPA, VAPB or MOSPD2. {ECO:0000269|PubMed:24105263, ECO:0000269|PubMed:29858488}. |
| Mouse PG classification | NA |
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