| Gene Information | |
|---|---|
| Gene Name | CA6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 308 |
| Protein Names | Carbonic anhydrase 6 (EC 4.2.1.1) (Carbonate dehydratase VI) (Carbonic anhydrase VI) (CA-VI) (Salivary carbonic anhydrase) (Secreted carbonic anhydrase) |
| Target Name | carbonic anhydrase |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000131686 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P23280 |
| Gene Card | CA6 |
| Uniprot ID | P23280 |
| Pfam | PF00194 |
| In ASD | no |
| Allosteric Prediction | no (-0.832581762) |
| Ortholog in Animals | Alpaca_ CA6 ( ortholog_one2one ) Dog_ CA6 ( ortholog_one2one ) Macaque_ CA6 ( ortholog_one2one ) Mouse_ Car6 ( ortholog_one2one ) Pig_ CA6 ( ortholog_one2one ) Rat_ Ca6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CA9, CA5B, CA1, CA8, CA2, CA12, CA7, CA14, CA3, CA13, CA4, CA5A, CA11, CA10 |
| Tissue | salivary.gland, parotid.gland |
| Tissue Specificity | Major constituent of saliva. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3FE4 (X-ray 1.90A ) |
| DBSNP | rs34265054 rs2274327 rs58800854 rs2274328 rs2274329 rs2274333 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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