| Gene Information | |
|---|---|
| Gene Name | SSTR4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 388 |
| Protein Names | Somatostatin receptor type 4 (SS-4-R) (SS4-R) (SS4R) (SST4) |
| Target Name | somatostatin receptor type 4 |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000132671 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P31391 |
| Gene Card | SSTR4 |
| Uniprot ID | P31391 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.539949735) |
| Ortholog in Animals | Alpaca_ SSTR4 ( ortholog_one2one ) Macaque_ SSTR4 ( ortholog_one2one ) Mouse_ Sstr4 ( ortholog_one2one ) Rat_ Sstr4 ( ortholog_one2one ) |
| Ohnologs | OPRK1, OPRM1, OPRD1, SSTR1, MCHR2 |
| Paralogs | SSTR5, NPBWR1, OPRL1, GPR149, OPRM1, OPRK1, PTGDR2, SSTR3, CMKLR2, SSTR1, LTB4R, LTB4R2, KISS1R, UTS2R, NPBWR2, SSTR2, OPRD1 |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7XMS (EM 2.90A ) 7XMT (EM 2.80A ) |
| DBSNP | rs1065191 rs35601930 rs3746726 rs2567608 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
| click here to return to the previous page | |