| Gene Information | |
|---|---|
| Gene Name | CA3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 260 |
| Protein Names | Carbonic anhydrase 3 (EC 4.2.1.1) (Carbonate dehydratase III) (Carbonic anhydrase III) (CA-III) |
| Target Name | carbonic anhydrase |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000164879 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P07451 |
| Gene Card | CA3 |
| Uniprot ID | P07451 |
| Pfam | PF00194 |
| In ASD | no |
| Allosteric Prediction | no (-0.169774575) |
| Ortholog in Animals | Alpaca_ CA3 ( ortholog_one2one ) Dog_ CA3 ( ortholog_one2one ) GuineaPig_ CA3 ( ortholog_one2one ) Macaque_ CA3 ( ortholog_one2one ) Mouse_ Car3 ( ortholog_one2one ) Pig_ CA3 ( ortholog_one2one ) Rat_ Ca3 ( ortholog_one2one ) Rabbit_ CA3 ( ortholog_one2one ) |
| Ohnologs | CA7, CA5B, CA5A |
| Paralogs | CA9, CA5B, CA1, CA8, CA2, CA12, CA7, CA14, CA13, CA4, CA5A, CA6, CA11, CA10 |
| Tissue | skeletal.muscle, artery, penis, lung, testis |
| Tissue Specificity | Muscle specific. {ECO:0000269|PubMed:3086182, ECO:0000269|PubMed:3099285}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1Z93 (X-ray 2.10A ) 1Z97 (X-ray 2.10A ) 2HFW (X-ray 2.50A ) 3UYN (X-ray 2.60A ) 3UYQ (X-ray 1.70A ) |
| DBSNP | rs20571 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18618712}. |
| Mouse PG classification | NA |
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