| Gene Information | |
|---|---|
| Gene Name | IL24 |
| Organism | Homo sapiens (Human) |
| Gene Length | 206 |
| Protein Names | Interleukin-24 (IL-24) (Melanoma differentiation-associated gene 7 protein) (MDA-7) (Suppression of tumorigenicity 16 protein) |
| Target Name | interleukin-24 |
| Target Type | Clinical trial target |
| Gene Age | 244 ( ENSG00000162892 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q13007 |
| Gene Card | IL24 |
| Uniprot ID | Q13007 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.336967972) |
| Ortholog in Animals | Alpaca_ IL24 ( ortholog_one2one ) Dog_ IL24 ( ortholog_one2one ) GuineaPig_ IL24 ( ortholog_one2one ) Macaque_ IL24 ( ortholog_one2one ) Mouse_ Il24 ( ortholog_one2one ) Pig_ IL24 ( ortholog_one2one ) Rat_ Il24 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IL20, IL19, IL10, IL26 |
| Tissue | appendix, lymph.node, spleen, tonsil, urinary.bladder |
| Tissue Specificity | Up-regulated in melanoma cells induced to terminally differentiate. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6DF3 (X-ray 2.15A ) 6GG1 (X-ray 1.30A ) |
| DBSNP | rs1150258 rs3093431 rs3093446 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:11706020}. |
| Mouse PG classification | NA |
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