| Gene Information | |
|---|---|
| Gene Name | CA11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 185 |
| Protein Names | Gastrokine-1 (18 kDa antrum mucosa protein) (AMP-18) (Protein CA11) |
| Target Name | carbonic anhydrase-related protein 11 |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000063180 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NS71 |
| Gene Card | GKN1 |
| Uniprot ID | Q9NS71 |
| Pfam | PF04089 |
| In ASD | no |
| Allosteric Prediction | no (-1.000104604) |
| Ortholog in Animals | Alpaca_ CA11 ( ortholog_one2one ) Dog_ CA11 ( ortholog_one2one ) GuineaPig_ CA11 ( ortholog_one2one ) Macaque_ CA11 ( ortholog_one2one ) Mouse_ Car11 ( ortholog_one2one ) Pig_ CA11 ( ortholog_one2one ) Rat_ Ca11 ( ortholog_one2one ) |
| Ohnologs | CA10 |
| Paralogs | CA9, CA5B, CA1, CA8, CA2, CA12, CA7, CA14, CA3, CA13, CA4, CA5A, CA6, CA10 |
| Tissue | NA |
| Tissue Specificity | Expressed in stomach (at protein level). No expression is detected in cancer tissue or gastric cancer cell lines. {ECO:0000269|PubMed:10835488, ECO:0000269|PubMed:12851218, ECO:0000269|PubMed:15221938}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:15221938}. Cytoplasmic granule {ECO:0000269|PubMed:15221938}. Golgi apparatus {ECO:0000305|PubMed:15221938}. Note=Shows abundant granular cytoplasmic staining, with perinuclear accentuation suggestive of the Golgi apparatus. {ECO:0000269|PubMed:15221938}. |
| Mouse PG classification | NA |
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