| Gene Information | |
|---|---|
| Gene Name | NAV1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1877 |
| Protein Names | Neuron navigator 1 (Pore membrane and/or filament-interacting-like protein 3) (Steerin-1) (Unc-53 homolog 1) (unc53H1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000134369 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8NEY1 |
| Gene Card | NAV1 |
| Uniprot ID | Q8NEY1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.252091486) |
| Ortholog in Animals | Alpaca_ NAV1 ( ortholog_one2one ) Dog_ NAV1 ( ortholog_one2one ) GuineaPig_ NAV1 ( ortholog_one2one ) Macaque_ NAV1 ( ortholog_one2one ) Mouse_ Nav1 ( ortholog_one2one ) Pig_ NAV1 ( ortholog_one2one ) Rat_ Nav1 ( ortholog_one2one ) Rabbit_ NAV1 ( ortholog_one2one ) |
| Ohnologs | NAV3, NAV2 |
| Paralogs | NAV2, NAV3 |
| Tissue | NA |
| Tissue Specificity | Broadly expressed at low levels. Expressed at high levels in heart, skeletal muscle and placenta. {ECO:0000269|PubMed:12062803, ECO:0000269|PubMed:12079279}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16849342 rs2820289 rs2292822 rs16849379 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton {ECO:0000250}. Note=Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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