| Gene Information | |
|---|---|
| Gene Name | IL11 |
| Organism | Homo sapiens (Human) |
| Gene Length | 199 |
| Protein Names | Interleukin-11 (IL-11) (Adipogenesis inhibitory factor) (AGIF) (Oprelvekin) |
| Target Name | interleukin-11 |
| Target Type | Clinical trial target |
| Gene Age | 454 ( ENSG00000095752 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P20809 |
| Gene Card | IL11 |
| Uniprot ID | P20809 |
| Pfam | PF07400 |
| In ASD | no |
| Allosteric Prediction | yes (0.051252483) |
| Ortholog in Animals | Alpaca_ IL11 ( ortholog_one2one ) Dog_ IL11 ( ortholog_one2one ) GuineaPig_ IL11 ( ortholog_one2one ) Macaque_ IL11 ( ortholog_one2one ) Mouse_ Il11 ( ortholog_one2one ) Pig_ IL11 ( ortholog_one2one ) Rat_ Il11 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4MHL (X-ray 2.09A ) 6O4O (X-ray 1.62A ) |
| DBSNP | rs4252576 rs4252548 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:1828438, ECO:0000269|PubMed:2145578}. |
| Mouse PG classification | NA |
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