| Gene Information | |
|---|---|
| Gene Name | C7orf27 |
| Organism | Homo sapiens (Human) |
| Gene Length | 821 |
| Protein Names | BRCA1-associated ATM activator 1 (BRCA1-associated protein required for ATM activation protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6PJG6 |
| Gene Card | BRAT1 |
| Uniprot ID | Q6PJG6 |
| Pfam | PF02985 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:16452482}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4IFI (X-ray 2.20A ) |
| DBSNP | rs17856488 rs1085307958 rs886039312 rs200502048 rs60152725 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16452482, ECO:0000269|PubMed:25631046}. Cytoplasm {ECO:0000269|PubMed:25631046}. Note=Present at double strand breaks (DSBs)following ionizing radiation treatment. The ubiquitinated form localizes in the nucleus in a NDFIP1-dependent manner. {ECO:0000269|PubMed:16452482, ECO:0000269|PubMed:25631046}. |
| Mouse PG classification | NA |
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