| Gene Information | |
|---|---|
| Gene Name | C6orf167 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1243 |
| Protein Names | Protein MMS22-like (Methyl methanesulfonate-sensitivity protein 22-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6ZRQ5 |
| Gene Card | MMS22L |
| Uniprot ID | Q6ZRQ5 |
| Pfam | PF14911; PF14910 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001990(Rat);0.02(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9374435 rs9481410 rs1737145 rs10484830 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:21055983, ECO:0000269|PubMed:21055984, ECO:0000269|PubMed:21113133}. Chromosome {ECO:0000269|PubMed:21055983, ECO:0000269|PubMed:21055984, ECO:0000269|PubMed:21113133, ECO:0000269|PubMed:27338793, ECO:0000269|PubMed:27797818}. Note=Localizes to DNA damage sites, accumulates at stressed replication forks (PubMed:21055983, PubMed:21055984, PubMed:27797818). Recruited to stalled or collapsed replication forks; directly binds replication protein A complex (RPA/RP-A)-coated single-stranded DNA (ssDNA) (PubMed:27797818). {ECO:0000269|PubMed:21055983, ECO:0000269|PubMed:21055984, ECO:0000269|PubMed:27797818}. |
| Mouse PG classification | NA |
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