| Gene Information | |
|---|---|
| Gene Name | C5AR2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 337 |
| Protein Names | C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000134830 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9P296 |
| Gene Card | C5AR2 |
| Uniprot ID | Q9P296 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | no (-0.181380064) |
| Ortholog in Animals | Alpaca_ C5AR2 ( ortholog_one2one ) Dog_ C5AR2 ( ortholog_one2one ) GuineaPig_ C5AR2 ( ortholog_one2one ) Macaque_ C5AR2 ( ortholog_one2one ) Mouse_ C5ar2 ( ortholog_one2one ) Pig_ C5AR2 ( ortholog_one2one ) Rat_ C5ar2 ( ortholog_one2one ) Rabbit_ C5AR2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | C5AR1, C3AR1, FPR3, GPR32, FPR2, FPR1, CMKLR1, GPR33 |
| Tissue | whole.blood |
| Tissue Specificity | Frontal cortex, hippocampus, hypothalamus, pons and liver. {ECO:0000269|PubMed:11090875, ECO:0000269|PubMed:11165367}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs149572881 rs150599989 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19615750}; Multi-pass membrane protein {ECO:0000269|PubMed:19615750}. |
| Mouse PG classification | NA |
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