| Gene Information | |
|---|---|
| Gene Name | CDK16 |
| Organism | Homo sapiens (Human) |
| Gene Length | 496 |
| Protein Names | Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1) |
| Target Name | cyclin-dependent kinase 16 |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000102225 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q00536 |
| Gene Card | CDK16 |
| Uniprot ID | Q00536 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.900203946) |
| Ortholog in Animals | Alpaca_ CDK16 ( ortholog_one2one ) GuineaPig_ CDK16 ( ortholog_one2one ) Macaque_ CDK16 ( ortholog_one2one ) Mouse_ Cdk16 ( ortholog_one2one ) Pig_ CDK16 ( ortholog_one2one ) Rat_ Cdk16 ( ortholog_one2one ) Rabbit_ CDK16 ( ortholog_one2one ) |
| Ohnologs | CDK17, CDK18 |
| Paralogs | CDK14, CDKL2, CDK5, CDKL3, CDK7, CDK3, CDK1, CDKL1, CDK19, CDKL5, CDK6, CDK15, CDK4, CDKL4, CDK2, CDK20, CDK9, CDK12, CDK8, CDK10, CDK11B, CDK11A, CDK13, CDK18, CDK17, PRPF4B |
| Tissue | NA |
| Tissue Specificity | Detected in pancreas islets (at protein level). Detected in brain and pancreas. {ECO:0000269|PubMed:22798068}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 3MTL (X-ray 2.40A ) 5G6V (X-ray 2.20A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Cytoplasmic vesicle, secretory vesicle. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Synapse, synaptosome {ECO:0000250}. Note=Colocalizes with insulin in pancreas islets. Recruited to the cell membrane by CCNY. |
| Mouse PG classification | NA |
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