| Gene Information | |
|---|---|
| Gene Name | AP1S3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 154 |
| Protein Names | AP-1 complex subunit sigma-3 (Adaptor protein complex AP-1 subunit sigma-1C) (Adaptor-related protein complex 1 subunit sigma-1C) (Clathrin assembly protein complex 1 sigma-1C small chain) (Golgi adaptor HA1/AP1 adaptin sigma-1C subunit) (Sigma 1C subunit of AP-1 clathrin) (Sigma-adaptin 1C) (Sigma1C-adaptin) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000152056 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96PC3 |
| Gene Card | AP1S3 |
| Uniprot ID | Q96PC3 |
| Pfam | PF01217 |
| In ASD | no |
| Allosteric Prediction | no (-0.750912814) |
| Ortholog in Animals | Alpaca_ AP1S3 ( ortholog_one2one ) GuineaPig_ AP1S3 ( ortholog_one2one ) Macaque_ AP1S3 ( ortholog_one2one ) Mouse_ Ap1s3 ( ortholog_one2one ) Pig_ AP1S3 ( ortholog_one2one ) Rat_ Ap1s3 ( ortholog_one2one ) Rabbit_ AP1S3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AP4S1, AP3S1, AP2S1, AP3S2, AP1S1, AP1S2 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4HMY (X-ray 7.00A ) 6CM9 (EM 3.73A ) 6CRI (EM 6.80A ) 6D83 (EM 4.27A ) 6D84 (EM 6.72A ) 6DFF (EM 3.90A ) |
| DBSNP | rs116107386 rs750870128 rs149183052 rs78536455 rs138292988 rs34353588 rs202157374 |
| Subcellular location [CC] | Golgi apparatus. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane, clathrin-coated pit. Note=Component of the coat surrounding the cytoplasmic face of coated vesicles located at the Golgi complex. |
| Mouse PG classification | NA |
| click here to return to the previous page | |