| Gene Information | |
|---|---|
| Gene Name | DDX21 |
| Organism | Homo sapiens (Human) |
| Gene Length | 547 |
| Protein Names | Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000165732 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NY93 |
| Gene Card | DDX56 |
| Uniprot ID | Q9NY93 |
| Pfam | PF00270; PF00271 |
| In ASD | no |
| Allosteric Prediction | yes (0.312880326) |
| Ortholog in Animals | Alpaca_ DDX21 ( ortholog_one2one ) Dog_ DDX21 ( ortholog_one2one ) GuineaPig_ DDX21 ( ortholog_one2one ) Macaque_ KIFBP ( ortholog_one2one ) Mouse_ Ddx21 ( ortholog_one2one ) Pig_ DDX21 ( ortholog_one2one ) Rat_ Ddx21 ( ortholog_one2one ) Rabbit_ DDX21 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DDX28, DDX42, DDX25, DDX47, DDX49, DDX20, DDX50, DDX41, DDX24, TDRD12, DDX5, DDX52, DDX56, DDX3X, DDX3Y, DDX59, DDX39B, DDX23, EIF4A3, DDX54, DDX10, DDX19A, DDX19B, EIF4A1, DDX6, DDX39A, DDX55, DDX18, DDX4, DDX1, DDX53, DDX17, DDX31, DDX51, DDX43, EIF4A2, DDX27, DDX46 |
| Tissue | NA |
| Tissue Specificity | Detected in heart, brain, liver, pancreas, placenta and lung. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:22925334, ECO:0000269|PubMed:31340999, ECO:0000269|PubMed:33789112}. |
| Mouse PG classification | NA |
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