| Gene Information | |
|---|---|
| Gene Name | C3AR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 482 |
| Protein Names | C3a anaphylatoxin chemotactic receptor (C3AR) (C3a-R) |
| Target Name | c3a anaphylatoxin chemotactic receptor |
| Target Type | Literature-reported target |
| Gene Age | 645 ( ENSG00000171860 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q16581 |
| Gene Card | C3AR1 |
| Uniprot ID | Q16581 |
| Pfam | PF00001 |
| In ASD | no |
| Allosteric Prediction | yes (1.040343048) |
| Ortholog in Animals | Alpaca_ C3AR1 ( ortholog_one2one ) Dog_ C3AR1 ( ortholog_one2one ) GuineaPig_ C3AR1 ( ortholog_one2one ) Macaque_ C3AR1 ( ortholog_one2one ) Mouse_ C3ar1 ( ortholog_one2one ) Rat_ C3ar1 ( ortholog_one2one ) Rabbit_ C3AR1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | C5AR1, C5AR2, FPR3, GPR32, FPR2, FPR1, CMKLR1, GPR33 |
| Tissue | NA |
| Tissue Specificity | Widely expressed in several differentiated hematopoietic cell lines, in the lung, spleen, ovary, placenta, small intestine, throughout the brain, heart, and endothelial cells. Mostly expressed in lymphoid tissues. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs11567806 |
| Subcellular location [CC] | Cell membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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