| Gene Information | |
|---|---|
| Gene Name | C20orf133 |
| Organism | Homo sapiens (Human) |
| Gene Length | 425 |
| Protein Names | ADP-ribose glycohydrolase MACROD2 (MACRO domain-containing protein 2) (O-acetyl-ADP-ribose deacetylase MACROD2) (EC 3.5.1.-) ([Protein ADP-ribosylaspartate] hydrolase MACROD2) (EC 3.2.2.-) ([Protein ADP-ribosylglutamate] hydrolase MACROD2) (EC 3.2.2.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | A1Z1Q3 |
| Gene Card | MACROD2 |
| Uniprot ID | A1Z1Q3 |
| Pfam | PF01661 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4IQY (X-ray 1.55A ) 6Y4Y (X-ray 1.75A ) 6Y4Z (X-ray 1.90A ) 6Y73 (X-ray 1.70A ) |
| DBSNP | rs2990505 rs41275442 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:23474712}. Note=Recruited to DNA lesions, probably via mono-APD-ribosylated proteins. {ECO:0000269|PubMed:23474712}. |
| Mouse PG classification | NA |
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