| Gene Information | |
|---|---|
| Gene Name | UBR4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 5183 |
| Protein Names | E3 ubiquitin-protein ligase UBR4 (EC 2.3.2.27) (600 kDa retinoblastoma protein-associated factor) (N-recognin-4) (RING-type E3 ubiquitin transferase UBR4) (Retinoblastoma-associated factor of 600 kDa) (RBAF600) (p600) (Zinc finger UBR1-type protein 1) |
| Target Name | e3 ubiquitin-protein ligase ubr4 |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000127481 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | NA |
| Gene Card | UBR4 |
| Uniprot ID | Q5T4S7 |
| Pfam | PF13764; PF19423; PF02207 |
| In ASD | no |
| Allosteric Prediction | no (-0.237867427) |
| Ortholog in Animals | Alpaca_ UBR4 ( ortholog_one2one ) Dog_ UBR4 ( ortholog_one2one ) GuineaPig_ UBR4 ( ortholog_one2one ) Macaque_ UBR4 ( ortholog_one2one ) Mouse_ Ubr4 ( ortholog_one2one ) Pig_ UBR4 ( ortholog_one2one ) Rat_ Ubr4 ( ortholog_one2one ) Rabbit_ UBR4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);0.015385(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs16862578 rs756549939 rs12584 rs2274010 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Concentrates at the leading edge of membrane structures involved in actin motility. |
| Mouse PG classification | NA |
| click here to return to the previous page | |