Gene Information
Gene NameSEMA6B
OrganismHomo sapiens (Human)
Gene Length888
Protein NamesSemaphorin-6B (Semaphorin-Z) (Sema Z)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000167680 )
Evolutionary StageEumetazoa
AlphaFoldDBQ9H3T3
Gene CardSEMA6B
Uniprot IDQ9H3T3
PfamPF01437; PF01403
In ASDno
Allosteric Predictionno (-1.435111073)
Ortholog in AnimalsAlpaca_ SEMA6B ( ortholog_one2one )
Dog_ SEMA6B ( ortholog_one2one )
GuineaPig_ SEMA6B ( ortholog_one2one )
Macaque_ SEMA6B ( ortholog_one2one )
Mouse_ Sema6b ( ortholog_one2one )
Pig_ SEMA6B ( ortholog_one2one )
Rat_ Sema6b ( ortholog_one2one )
OhnologsSEMA6A, SEMA5A, SEMA6D, SEMA6C, SEMA4B, SEMA4D, SEMA4A
ParalogsSEMA4D, SEMA6D, SEMA3A, SEMA3F, SEMA6C, SEMA3E, SEMA3D, SEMA4B, SEMA4F, SEMA3B, SEMA4G, SEMA3C, SEMA5A, SEMA4A, SEMA5B, SEMA7A, SEMA3G, SEMA4C, SEMA6A
TissueNA
Tissue SpecificityExpressed in the brain in GABAergic neurons. {ECO:0000269|PubMed:32169168}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:32302524};
Single-pass type I membrane protein {ECO:0000255}.
Mouse PG classificationNA
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