| Gene Information | |
|---|---|
| Gene Name | EXO5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 373 |
| Protein Names | Exonuclease V (Exo V) (hExo5) (EC 3.1.-.-) (Defects in morphology protein 1 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164002 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H790 |
| Gene Card | EXO5 |
| Uniprot ID | Q9H790 |
| Pfam | PF09810 |
| In ASD | no |
| Allosteric Prediction | no (-1.136569824) |
| Ortholog in Animals | Alpaca_ EXO5 ( ortholog_one2one ) Dog_ EXO5 ( ortholog_one2one ) GuineaPig_ EXO5 ( ortholog_one2one ) Macaque_ EXO5 ( ortholog_one2one ) Mouse_ Exo5 ( ortholog_one2one ) Pig_ EXO5 ( ortholog_one2one ) Rat_ Exo5 ( ortholog_one2one ) Rabbit_ EXO5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7LW7 (X-ray 2.50A ) 7LW8 (X-ray 2.88A ) 7LW9 (X-ray 2.71A ) 7LWA (X-ray 2.85A ) |
| DBSNP | rs1134586 rs11208299 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:23095756}. Cytoplasm, cytosol {ECO:0000269|PubMed:23095756}. Note=Localizes to repair foci in response to DNA damage. |
| Mouse PG classification | NA |
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