| Gene Information | |
|---|---|
| Gene Name | AGBL5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 886 |
| Protein Names | Cytosolic carboxypeptidase-like protein 5 (EC 3.4.17.-) (EC 3.4.17.24) (ATP/GTP-binding protein-like 5) (Protein deglutamylase CCP5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000084693 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8NDL9 |
| Gene Card | AGBL5 |
| Uniprot ID | Q8NDL9 |
| Pfam | PF18027; PF00246 |
| In ASD | no |
| Allosteric Prediction | no (-0.941760442) |
| Ortholog in Animals | Alpaca_ AGBL5 ( ortholog_one2one ) Dog_ AGBL5 ( ortholog_one2one ) GuineaPig_ AGBL5 ( ortholog_one2one ) Macaque_ AGBL5 ( ortholog_one2one ) Mouse_ Agbl5 ( ortholog_one2one ) Pig_ AGBL5 ( ortholog_one2one ) Rat_ Agbl5 ( ortholog_one2one ) Rabbit_ AGBL5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | AGBL3, AGTPBP1, AGBL4, AGBL1, AGBL2 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs879253769 rs780394281 rs879253768 rs35804461 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q09M02}. Nucleus {ECO:0000269|PubMed:23085998}. Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:23085998}. Midbody {ECO:0000269|PubMed:23085998}. Note=Mainly cytoplasmic. Slight accumulation in the nucleus is observed (By similarity). Colocalizes with alpha-tubulin in the mitotic spindle and with midbody microtubules in the intercellular bridges formed during cytokinesis. {ECO:0000250|UniProtKB:Q09M02, ECO:0000269|PubMed:23085998}. |
| Mouse PG classification | NA |
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