| Gene Information | |
|---|---|
| Gene Name | TAX1BP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 789 |
| Protein Names | Tax1-binding protein 1 (TRAF6-binding protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000106052 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q86VP1 |
| Gene Card | TAX1BP1 |
| Uniprot ID | Q86VP1 |
| Pfam | PF07888; PF17751; PF18112 |
| In ASD | no |
| Allosteric Prediction | no (-0.744757437) |
| Ortholog in Animals | Alpaca_ TAX1BP1 ( ortholog_one2one ) Dog_ TAX1BP1 ( ortholog_one2one ) GuineaPig_ TAX1BP1 ( ortholog_one2one ) Macaque_ TAX1BP1 ( ortholog_one2one ) Mouse_ Tax1bp1 ( ortholog_one2one ) Pig_ TAX1BP1 ( ortholog_one2one ) Rat_ Tax1bp1 ( ortholog_one2one ) Rabbit_ TAX1BP1 ( ortholog_one2one ) |
| Ohnologs | CALCOCO1 |
| Paralogs | CALCOCO1, CALCOCO2 |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues tested. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001445(Rat);0.035624(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2M7Q (NMR - ) 4BMJ (X-ray 2.75A ) 4NLH (X-ray 1.90A ) 4Z4K (X-ray 2.80A ) 4Z4M (X-ray 2.15A ) 5AAS (NMR - ) 5YT6 (X-ray 1.50A ) 5Z7G (X-ray 2.30A ) |
| DBSNP | rs7809260 rs11540483 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:30909570}. Mitochondrion {ECO:0000269|PubMed:27736772}. Preautophagosomal structure {ECO:0000269|PubMed:33226137, ECO:0000269|PubMed:34471133}. Cytoplasmic vesicle, autophagosome {ECO:0000269|PubMed:26451915}. |
| Mouse PG classification | NA |
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