| Gene Information | |
|---|---|
| Gene Name | KIAA1652 |
| Organism | Homo sapiens (Human) |
| Gene Length | 524 |
| Protein Names | Thioredoxin reductase 2, mitochondrial (EC 1.8.1.9) (Selenoprotein Z) (SelZ) (TR-beta) (Thioredoxin reductase TR3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | NA |
| Gene Card | TXNRD2 |
| Uniprot ID | Q9NNW7 |
| Pfam | PF07992; PF02852 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690). {ECO:0000269|PubMed:10215850, ECO:0000269|PubMed:10608886, ECO:0000269|PubMed:24601690, ECO:0000269|PubMed:9923614}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs45593642 rs5748469 rs5992495 rs1139793 |
| Subcellular location [CC] | Mitochondrion {ECO:0000269|PubMed:10215850}. |
| Mouse PG classification | NA |
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